SAC2 Rabbit Polyclonal Antibody, 100ul Variant Libraries Signaling by Notch receptors mediates

Signaling by Notch receptors mediates a wide range of developmental cell fates

where amino acid sequence is highly conserved between members and throughout evolution

The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits

and glycogen synthase kinase-3 (GSK-3) signaling pathways

Not found in liver and lung

SAC2 Rabbit Polyclonal Antibody, 100ul Variant Libraries Signaling by Notch receptors mediatesThe protein encoded by this gene is an inositol 1 4 5 trisphosphate (InsP3) 5 phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4 5 bisphosphate and phosphatidylinositol 3 4 5 trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.