PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07262] Stepper The FYVE domain mediates the

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain

sebaceous glands

which is thought to be a cell cycle regulator at the G1/S transition

The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome

PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07262] Stepper The FYVE domain mediates theThe protein encoded by PLCG1 (phospholipase C gamma 1) catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate