SPR2D Rabbit Polyclonal Antibody, 50ul Antibody Humanization Mutations in this gene are

Mutations in this gene are a cause of colorectal cancer (CRC)| pilomatrixoma (PTR)| medulloblastoma (MDB)| and ovarian cancer

This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins

The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins

alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-

We also provide products focused for use in molecular hybridization and PCR such as TaqMan/MGB qPCR probes

SPR2D Rabbit Polyclonal Antibody, 50ul Antibody Humanization Mutations in this gene are