JAK2(Phospho Tyr570) Polyclonal Antibody, 50ul Reservoirs Several alternatively spliced transcripts have

Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins

Mutations in NME1 have been identified in aggressive neuroblastomas

May play an important role in cell proliferation and/or anti-apoptosis

Widely expressed with highest expression in testis and lower expression in thymus

Protein Wnt-16 have been implicated in oncogenesis and in several developmental processes

JAK2(Phospho Tyr570) Polyclonal Antibody, 50ul Reservoirs Several alternatively spliced transcripts haveThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.