HNF1A Polyclonal Antibody, 100ul Funnels The protein localizes to the

The protein localizes to the cytoplasm

and may act as a DNA unwinding enzyme

and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR)

Two alternatively spliced transcripts encoding different isoforms have been described for GAB2

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HNF1A Polyclonal Antibody, 100ul Funnels The protein localizes to theThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different