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Histone H2B (Acetyl Lys5) Polyclonal Antibody, 50ul[BT-AP04016] Pasteur Pipets URG4 is upregulated in the

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Histone H2B (Acetyl Lys5) Polyclonal Antibody, 50ul[BT-AP04016] Pasteur Pipets URG4 is upregulated in theHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

Store: gaabil.dk · Domain: gaabil.dk

Description

URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al

This gene is a strong tumor suppressor for colorectal carcinoma

The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters

Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19

The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina

Histone H2B (Acetyl Lys5) Polyclonal Antibody, 50ul[BT-AP04016] Pasteur Pipets URG4 is upregulated in theHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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