SEGN Polyclonal Antibody, 100ul Cell Separation and Collection Mutations in KRT10 are associated

Mutations in KRT10 are associated with epidermolytic hyperkeratosis

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family

GO annotations related to this gene include nucleic acid binding and chromatin binding

AP-1 transcription factor subunit which is highly similar to the viral protein

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors

SEGN Polyclonal Antibody, 100ul Cell Separation and Collection Mutations in KRT10 are associatedThe encoded protein is a secreted calcium binding protein which is found in the cytoplasm. It is related to calbindin D 28K and calretinin. This protein is thought to be involved in KCL stimulated calcium flux and cell proliferation.