CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Mutations in this gene result

Mutations in this gene result in one form of autosomal dominant hearing impairment

Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance

and pluripotency

SFSWAP encodes a human homolog of Drosophila splicing regulatory protein

and three alternative downstream AUG initiation codons

CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Mutations in this gene resultThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.