ORC1 Polyclonal Antibody, 100ul Syringe Filter the encoded protein may contribute

the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients

and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs

Mouse studies suggested an essential role of this protein in spermatogenesis

This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling

together with its associated proteins

ORC1 Polyclonal Antibody, 100ul Syringe Filter the encoded protein may contributeORC1 encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. Origin recognition complex subunit 1 contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.