CUX2 Polyclonal Antibody, 50ul Serological Pipets cell-autonomous apoptosis of cerebellar Purkinje

cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development

The encoded protein is important in the regulation of genes involved in immune and inflammatory responses

Mutations in this gene are associated with Crouzon syndrome

stimulates dissociation of TOP1 from DNA after cleavage and enhances its jumping between separate DNA helices

Among its related pathways are Signaling by GPCR and Immune System

CUX2 Polyclonal Antibody, 50ul Serological Pipets cell-autonomous apoptosis of cerebellar PurkinjeThis gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA binding motifs. A similar gene, whose gene product possesses different DNA binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4.