FBX6 Rabbit Polyclonal Antibody, 100ul Centrifuges Mutations in VAMP1 are associated

Mutations in VAMP1 are associated with autosomal dominant spastic ataxia 1

The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex

They are thought to play roles in acyl-CoA dependent lipid metabolism

It also stimulates prostacyclin production and cell adhesion

These cytosolic enzymes are different in their tissue distributions and substrate specificities

FBX6 Rabbit Polyclonal Antibody, 100ul Centrifuges Mutations in VAMP1 are associatedThis gene encodes a member of the F box protein family which is characterized by an approximately 40 amino acid motif the F box. The F box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs containing