PKN1 Polyclonal Antibody, 50ul Mammalian Expression tissue specificity:In a wide range

tissue specificity:In a wide range of cell types

but not isoform 3

The protein encoded by this gene is a member of the shugoshin family of proteins

modifier of

Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders

PKN1 Polyclonal Antibody, 50ul Mammalian Expression tissue specificity:In a wide rangeThe protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3 phosphoinositide dependent protein kinase 1 (PDPK1 PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic