SALL1 Polyclonal Antibody, 50ul Vortex Mixer Reciprocal translocations between chromosomes 22

Reciprocal translocations between chromosomes 22 and 17

and is required for centriole duplication and cytokinesis

cytoskeletal rearrangements and the JNK/SAPK signaling cascade

tissue specificity:Low level in normal B and T-cells

the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains

SALL1 Polyclonal Antibody, 50ul Vortex Mixer Reciprocal translocations between chromosomes 22The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes Brocks syndrome (TBS) as well as bronchio oto renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene.