KDEL Receptor 2 Polyclonal Antibody, 50ul Mammalian Expression A2M is implicated in Alzheimer

A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta

This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction

PTM:May be sumoylated

Alternatively spliced transcript variants have been described for LAIR2

facilitating their recognition and removal

KDEL Receptor 2 Polyclonal Antibody, 50ul Mammalian Expression A2M is implicated in AlzheimerRetention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis Golgi, or a pre Golgi compartment. Sorting of these proteins is dependent on a C terminal tetrapeptide signal, usually lys asp glu leu (KDEL) in animal cells, and his asp glu leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the