MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter A gene encoding a similar

A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17

Telomerase Inhibitor 1) is a Protein Coding gene

Most isoforms share a common C-terminal domain

Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter A gene encoding a similarThe protein encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.