SIK1 Polyclonal Antibody, 20ul[BT-AP14227] Molecular Biology This gene encodes a G

This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily

The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor

Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18

Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene

Deregulation of telomerase expression in somatic cells may be involved in oncogenesis

SIK1 Polyclonal Antibody, 20ul[BT-AP14227] Molecular Biology This gene encodes a GCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Thr 182 by STK11 in complex with STE20 related adapter alpha (STRAD alpha) pseudo kinase and CAB39.,Transient role during the earliest stages of myocardial cell differentiation and or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and or differentiation. Potential