FKB1A Polyclonal Antibody, 50ul Antibodies genomic imprinting

genomic imprinting

Mutations in this gene cause dyskeratosis congenita (DKC)

The gene product belongs to the TF2B family

AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences

while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly

FKB1A Polyclonal Antibody, 50ul Antibodies genomic imprintingThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF beta receptor. It also interacts with multiple intracellular calcium