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PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Several alternatively spliced transcript variants

SKU: 88525901458

4.3
PLN141.00 PLN179.00

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PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Several alternatively spliced transcript variantsdisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM:

Store: gaabil.dk · Domain: gaabil.dk

Description

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

Upon activation of the alternative pathway

100% integrity test Sterilized and non-sterilized available

The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit

The protein (ataxin 2) encoded by ATXN2 has two globular domains near the N-terminus

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Several alternatively spliced transcript variantsdisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM:

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