NFκB-p65(Phospho Thr435) Polyclonal Antibody, 50ul Modified Oligos Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been described for PARD3

The A-I and A-IV genes are transcribed from the same strand

TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components

Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis

Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain| although some members contain only the sterol-binding domain

NFκB-p65(Phospho Thr435) Polyclonal Antibody, 50ul Modified Oligos Multiple alternatively spliced transcript variantsNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four