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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The encoded protein is a

SKU: 87221824854

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SEK162.00 SEK198.00

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The encoded protein is aThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

Store: gaabil.dk · Domain: gaabil.dk

Description

The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases

CYP3A7 encodes a member of the cytochrome P450 superfamily of enzymes

and in primary human tumors and cancer cell lines

It was originally isolated from Xenopus based on its ability to restore normal dorsal-ventral body axis in embryos that had been artificially ventralized by UV treatment

motility or function

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The encoded protein is aThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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