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EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein may be

SKU: 87148221178

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EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein may beThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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Description

The encoded protein may be involved in endosome-to-Golgi transport

and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors

Alternative splicing results in multiple trans

IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells

This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients

EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein may beThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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