Kininogen 1 Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging Reduced expression of GDF9 may

Reduced expression of GDF9 may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins

are a family of type 1 transmembrane proteins each having a unique expression pattern

HNRP proteins have also been identified outside of the nucleoplasm

The encoded protein is involved in several cellular processes| including autophagic vesicle formation| mitochondrial quality control after oxidative damage| negative regulation of the innate antiviral immune response| lymphocyte development and proliferation| MHC II antigen presentation| adipocyte differentiation| and apoptosis

The protein encoded by this gene belongs to the protein kinase C superfamily

Kininogen 1 Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging Reduced expression of GDF9 mayThis gene uses alternative splicing to generate two different proteins high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is