PI4KA Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Three alternatively spliced transcript variants

Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified

|Contains 1 PA (protease associated) domain

This kinase was reported to interact with

The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport

Mutations in this gene cause autosomal dominant spastic paraplegia 10

PI4KA Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Three alternatively spliced transcript variantsThis gene encodes a phosphatidylinositol (PI) 4 kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4 5 bisphosphate. The mammalian PI 4 kinases have been classified into two types II and III based on their molecular mass and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine.