GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity

deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium

recognizing nonreducing terminal sugars and their anomeric linkages

The integrin subunit beta 2 plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency

This gene encodes a protein that contains a DNA-binding domain

GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates Gene Ontology (GO) annotations relatedThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.