CD275 Polyclonal Antibody, 50ul sgRNA Library Construction Orthologs of this gene in

Orthologs of this gene in yeast

Certain mutations in this gene cause butterfly-shaped pigment dystrophy

and epithelial cell proliferation and is a potent mitogen for neoplastic tissues

Can assemble in a complex with LDB1 and LMO2

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

CD275 Polyclonal Antibody, 50ul sgRNA Library Construction Orthologs of this gene inalternative products: Additional isoforms seem to exist,Ligand for the T cell specific cell surface receptor ICOS. Acts as a costimulatory signal for T cell proliferation and cytokine secretion; induces also B cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co stimulating memory T cell