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PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection Overexpression of PMEPA1 may play

SKU: 86162460842

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PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection Overexpression of PMEPA1 may playPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

Store: gaabil.dk · Domain: gaabil.dk

Description

Overexpression of PMEPA1 may play a role in multiple types of cancer

The CCAAT/enhancer binding protein epsilon encoded by CEBPE is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions

The type II keratins are clustered in a region of chromosome 12q13

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT)

Diseases associated with SUPT3H include blastic plasmacytoid dendritic cell

PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection Overexpression of PMEPA1 may playPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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