Neu Polyclonal Antibody, 100ul[BT-AP05901] Filtration the IAN subfamily genes are

the IAN subfamily genes are located in a cluster at 7q36

There are multiple pseudogenes of this gene on different chromosomes

which promotes binding by heat shock protein 90

Alternative splicing results in multiple transcript variants that encode multiple protein isoforms

The protein encoded by this gene is conserved across vertebrates and may play an essential role during development

Neu Polyclonal Antibody, 100ul[BT-AP05901] Filtration the IAN subfamily genes areERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Erb b2 receptor tyrosine kinase 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving