TXLNA Polyclonal Antibody, 20ul Gene Editing Overexpression of PDK2 may play

Overexpression of PDK2 may play a role in both cancer and diabetes

The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription

May be involved in NF-kappa-B and MAPK signaling pathways

Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II)

Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome

TXLNA Polyclonal Antibody, 20ul Gene Editing Overexpression of PDK2 may playWas originally (PubMed: 8327514) thought to be a high molecular weight interleukin (IL 14 or IL14).,May be involved in intracellular vesicle traffic and potentially in calcium dependent exocytosis in neuroendocrine cells.,Belongs to the taxilin family.,subunit: Binds to the C terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it