DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 100ul Custom Peptide Synthesis The encoded protein is a

The encoded protein is a cytokine produced in response to viral infection

it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production

Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders

It may play a role in signal transduction cascades in terminally differentiated cells

Pseudogenes of this gene have been defined on chromosomes 1

DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 100ul Custom Peptide Synthesis The encoded protein is aThe protein encoded by this gene is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4