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TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing POLD3 encodes the 66-kDa subunit

SKU: 84502679206

4.7
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TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing POLD3 encodes the 66-kDa subunitThis gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C terminal Myb motif, a dimerization domain near its N terminus and an acidic N terminus. Two transcripts of this gene are alternatively

Store: gaabil.dk · Domain: gaabil.dk

Description

POLD3 encodes the 66-kDa subunit of DNA polymerase delta

Also it may be involved in signal transduction

Alternative splicing of this gene results in three transcript variants encoding distinct isoforms

and for interaction with anti-apoptotic members of the BCL2 family

The protein (ankyrin repeat domain 1) encoded by ANKRD1 is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation

TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing POLD3 encodes the 66-kDa subunitThis gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C terminal Myb motif, a dimerization domain near its N terminus and an acidic N terminus. Two transcripts of this gene are alternatively

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