Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes a protein kinase domain

a protein kinase domain

This protein is also thought to modify lipid metabolism and insulin-regulated gene expression

These family members contain multiple N-terminal leucine-rich repeats| in addition to a C-terminal calponin homology domain| a type of domain that mediates interactions with actin filaments

The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation

The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman

Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes a protein kinase domainAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone