Proteasome alpha3 Rabbit Polyclonal Antibody, 50ul Capsule Filter EV is caused by mutations

EV is caused by mutations in either of two adjacent genes located on chromosome 17q25

The protein encoded by AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation

Alternatively splicing results in multiple transcript variants| including the DM20 splice variant

|subunit:Binds to the receptor tyrosine kinases EPHA2| EPHA4| EPHA5| EPHA6 and EPHA7

CASP4 encodes caspase 4 that is a member of the cysteine-aspartic acid protease (caspase) family

Proteasome alpha3 Rabbit Polyclonal Antibody, 50ul Capsule Filter EV is caused by mutationsThe proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP ubiquitin dependent process in a non lysosomal pathway. An essential function