GATA-1 (Acetyl Lys312) Rabbit Polyclonal Antibody, 20ul Palm Micro Centrifuges NFAT proteins are activated by

NFAT proteins are activated by the calmodulin-dependent phosphatase| calcineurin

Component of the probable ECS(SPSB2) complex with the substrate recognition component SPSB2

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding

suggesting a link with Alzheimer disease

GATA-1 (Acetyl Lys312) Rabbit Polyclonal Antibody, 20ul Palm Micro Centrifuges NFAT proteins are activated bydisease: Defects in GATA1 are the cause of X linked dyserythropoietic anemia and thrombocytopenia (XDAT)