DIAP2 Polyclonal Antibody, 20ul[BT-AP15237] Sampling Tubes ARRDC3 (arrestin domain containing 3)

ARRDC3 (arrestin domain containing 3) encodes a member of the arrestin family of proteins

The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW)

Yeast Rad18 functions through its interaction with Rad6| which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA

DIAP2 Polyclonal Antibody, 20ul[BT-AP15237] Sampling Tubes ARRDC3 (arrestin domain containing 3)The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified.