EDEM1 Polyclonal Antibody, 20ul ssDNA Synthesis a highly penetrant familial cancer

a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53

resulting in expression of a chimeric protein

Interleukin-28 receptor subunit alpha encoded by IFNLR1 belongs to the class II cytokine receptor family

Dihydropyrimidine dehydrogenase [NADP(+)] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism

and is subject to RNA editing (AGA->GGA

EDEM1 Polyclonal Antibody, 20ul ssDNA Synthesis a highly penetrant familial cancerExtracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N glycan dependent manner. It lacks mannosidase activity.,Belongs to the glycosyl hydrolase 47 family.,subunit: Interacts with DERL2 and DERL3.,