Cyclin B1(Phospho Ser147) Polyclonal Antibody, 50ul Endonucleases & Exonucleases Mutations in this gene are

Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8

This gene encodes a PDZ domain-containing protein

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK)| MAPK kinase (MKK or MEK)| and MAPK kinase kinase (MAPKKK or MEKK)

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pRB suppresses cellular proliferation and is inactivated

Cyclin B1(Phospho Ser147) Polyclonal Antibody, 50ul Endonucleases & Exonucleases Mutations in this gene areThe protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle regulated transcript, that is expressed predominantly during G2 M phase. The different transcripts result from the use of alternate transcription initiation sites.