Ku-70 Polyclonal Antibody, 100ul[BT-AP04895] Cell Proliferation Additional alternatively spliced transcript variants

Additional alternatively spliced transcript variants have been described for SRPK1

Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia

Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein

It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction

Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase

Ku-70 Polyclonal Antibody, 100ul[BT-AP04895] Cell Proliferation Additional alternatively spliced transcript variantsThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with