CAPS2 Polyclonal Antibody, 100ul Drug Development and Evaluation Insulin gene enhancer protein ISL-2

Insulin gene enhancer protein ISL-2 is a transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways

It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins

Mutations in SLC4A11 have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2

transcriptional activation and cell cycle progression

and functions as an important regulator of multiple signaling pathways in hematopoietic cells

CAPS2 Polyclonal Antibody, 100ul Drug Development and Evaluation Insulin gene enhancer protein ISL-2This gene encodes a member of the calcium dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.