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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments subunit:Interacts with MKL1 and SRF

SKU: 82028813953

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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments subunit:Interacts with MKL1 and SRFThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Store: gaabil.dk · Domain: gaabil.dk

Description

subunit:Interacts with MKL1 and SRF

Mutations in SYN1 may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome

May function in transmigration of leukocytes through epithelial and endothelial tissues

This cyclin and its kinase partner are components of TFIIH

Nibrin is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins

Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments subunit:Interacts with MKL1 and SRFThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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