Stat5a Polyclonal Antibody, 20ul[BT-AP08639] Peptide Modification This transient expression of Rudhira

This transient expression of Rudhira is also seen in normal adult angiogenesis

This protein acts to integrate signals from ATM and ATR

thought to be related to the cytochrome c-mediated cell death pathway

The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form

Src family tyrosine kinase associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein

Stat5a Polyclonal Antibody, 20ul[BT-AP08639] Peptide Modification This transient expression of RudhiraStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.