RAB5B Polyclonal Antibody, 100ul Plates & Dishes Mutations in THBD are a

Mutations in THBD are a cause of thromboembolic disease

The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism

Insulin-like growth factor-binding protein 1 binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma

2009 [PubMed 19481526])

subcellular location:In unstimulated cells

RAB5B Polyclonal Antibody, 100ul Plates & Dishes Mutations in THBD are aenzyme regulation: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,Protein transport. Probably involved in vesicular traffic.,Belongs to the small GTPase superfamily. Rab family.,subcellular location: Enriched in stage I melanosomes.,subunit: Binds EEA1. Interacts with RIN2 and RIN3, which probably regulate its pathway, possibly by acting as GEFs.,