Phospho-BLM (T99) Polyclonal Antibody, 50ul Bio-Reaction Tube Tyrosine protein kinases are important

Tyrosine protein kinases are important regulators of intracellular signal transduction pathways| mediating cellular proliferation| survival| and development

This gene encodes a member of the desmocollin protein subfamily

Members of this family have diverse functions

It has histone deacetylase activity and represses transcription when tethered to a promoter

Diseases associated with CNTD2 include cataract 27

Phospho-BLM (T99) Polyclonal Antibody, 50ul Bio-Reaction Tube Tyrosine protein kinases are importantThe Bloom syndrome gene product is related to the RecQ subset of DExH box containing DNA helicases and has both DNA stimulated ATPase and ATP dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3' 5' helicase activity. The normal protein may act to suppress inappropriate recombination.