DSE Rabbit Polyclonal Antibody, 100ul Centrifuges down-regulated by phorbol 12-myristate 13-acetate

down-regulated by phorbol 12-myristate 13-acetate

This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes

This gene has multiple transcript variants which are predicted to encode distinct isoforms

DSE Rabbit Polyclonal Antibody, 100ul Centrifuges down-regulated by phorbol 12-myristate 13-acetateThe protein encoded by this gene is a tumor rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D glucuronic acid to L iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA A24 restricted and tumor specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural