P3C2A Polyclonal Antibody, 20ul Peptide Synthesis Rac GTPase activating protein 1

Rac GTPase activating protein 1 plays a regulatory role in cytokinesis

Alternatively spliced transcript variants encoding different isoforms have been described

This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates

CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development

Mutations in this gene have been associated with hepatocellular carcinoma

P3C2A Polyclonal Antibody, 20ul Peptide Synthesis Rac GTPase activating protein 1The protein encoded by this gene belongs to the phosphoinositide 3 kinase (PI3K) family. PI3 kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C terminal C2 domain, a characteristic of class II PI3 kinases. C2 domains act as calcium dependent phospholipid binding