PDC6I Polyclonal Antibody, 50ul Cryopreservation Three transcript variants encoding three

Three transcript variants encoding three different isoforms have been found for this gene

This protein is functionally conserved in its capacity to release the vasoactive peptide

However| the requirement for furin cleavage in this process remains controversial based on mouse studies

The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor

The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex

PDC6I Polyclonal Antibody, 50ul Cryopreservation Three transcript variants encoding threeThis gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium dependent manner. This gene product also binds to