Cdc2 Monoclonal Antibody, 50ul[BT-MCA0325] Recombinant Protein Mutations in EPHA2 are the

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity

The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex

among other genes

This protein forms a complex with another family member

Cdc2 Monoclonal Antibody, 50ul[BT-MCA0325] Recombinant Protein Mutations in EPHA2 are theThe protein encoded by this gene is a member of the Ser Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M phase promoting factor (MPF), which is essential for G1 S and G2 M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and