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It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4

Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin

Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini

Increased expression of this gene is associated with pancreatic cancer

TRI41 Rabbit Polyclonal Antibody, 20ul Sealing Film Transform your lab experiments withThis gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger one or more B box domains and a coiled coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene.