ERK1 mouse Monoclonal Antibody(4G11), 100ul Molecular Sciences |cofactor:Binds 2 magnesium ions per

|cofactor:Binds 2 magnesium ions per subunit

Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary

Low levels in placenta| prostate and small intestine

but not isoform 3

This motif is important for interaction with SKP1 and for targeting some proteins for degradation

ERK1 mouse Monoclonal Antibody(4G11), 100ul Molecular Sciences |cofactor:Binds 2 magnesium ions perThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear