ITGAV Rabbit Polyclonal Antibody, 20ul Live Cell Imaging SMAD proteins are signal transducers

SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways

Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416)

and its product S1P

and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I

An important paralog of this gene is GPR21

ITGAV Rabbit Polyclonal Antibody, 20ul Live Cell Imaging SMAD proteins are signal transducersThe product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1 beta 3 beta 5 beta 6 and beta 8 subunits. The heterodimer consisting