ANFC Polyclonal Antibody, 50ul Drug Development and Evaluation The C-terminus of the precursor

The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1

The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain

ATP5S encodes a subunit of mitochondrial ATP synthase

The encoded protein stabilizes the ORC and therefore aids in DNA replication

This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus

ANFC Polyclonal Antibody, 50ul Drug Development and Evaluation The C-terminus of the precursorThis gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP 53, CNP 29 and CNP 22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP 22 have been observed in the plasma of chronic heart failure patients.